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Pen storage lookup

How long can Ozempic stay out of the fridge? Can Wegovy be left out overnight? What room temperature does Mounjaro allow? There is no single answer for “GLP-1 pens” — the window is set by the brand and by the presentation on your carton, and the numbers are not close to each other. An Ozempic pen is allowed 56 days out of the fridge after first use. A Zepbound single-dose pen is allowed 21 days in total. A Rybelsus tablet is never refrigerated at all.

So this page does one thing: it shows you the wording from the current FDA label for the exact presentation you carry, with the label’s own revision date and a link to the label itself. Nothing here is rounded, averaged or summarised into a rule of thumb, and nothing here touches doses.

Your context

Two optional answers. They decide which boundary this page shows you, never what a label says. Stored in this browser only, and erasable on your device page.

Where you are
How you take it

Applies toUnited States FDA labels. Every storage line we publish is transcribed from the brand's own US prescribing information, with that document's revision date beside it.

Compounded semaglutide and tirzepatide are not FDA-approved products, so there is no approved label for us to quote (FDA, Compounding and the FDA: Questions and Answers, 2025). Follow the storage instructions from the pharmacy that compounded yours, and ask them anything this page does not answer.

What your label saysEvery number below is transcribed from the manufacturer's own FDA label — and your carton wins if it differs.

The label this row came from was revised 5/2026. Read the leaflet in your own carton, and ask your pharmacist if the two do not agree. Compounded products have no FDA-approved label, so nothing on this page applies to them.

LeanFed never covers dosing or timing.

What you carry

A pen, a KwikPen, a vial and a tablet are different rows. They are not interchangeable on storage.

Showing the label for Ozempic · Single-patient-use pen (multiple weekly doses) · label revised 5/2026.

label5/2026semaglutide

OzempicSingle-patient-use pen (multiple weekly doses)

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F) until the expiration date. Do not store in the freezer or directly next to the refrigerator's cooling element. Keep the pen in its original carton until you use it.
After first use
The pen can be kept for 56 days, either at controlled room temperature 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Keep the pen cap on when it is not in use, and store it with no needle attached.
Room-temperature window
56 days after first use, at 15°C to 30°C (59°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from excessive heat and sunlight. Keep in the original carton until the time of administration.
Label date
Revised 5/2026

Transcribed from the manufacturer’s current prescribing information. Read the label on DailyMed

Call your prescriber todayA pen that has been frozen, or left out past its window, is a phone call — not a judgement call.

Your pharmacist is the one who can tell you whether a particular pen is still usable, and your prescriber is the one to ask about anything to do with a dose you have missed, delayed or changed. We will not guess at either, and neither should a forum.

Every row, in full

The complete table, so you can read it without picking anything. Each row is transcribed from the label linked at the end of it.

semaglutide

OzempicSingle-patient-use pen (multiple weekly doses)

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F) until the expiration date. Do not store in the freezer or directly next to the refrigerator's cooling element. Keep the pen in its original carton until you use it.
After first use
The pen can be kept for 56 days, either at controlled room temperature 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Keep the pen cap on when it is not in use, and store it with no needle attached.
Room-temperature window
56 days after first use, at 15°C to 30°C (59°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from excessive heat and sunlight. Keep in the original carton until the time of administration.
Label date
Revised 5/2026

Read the Ozempic label on DailyMed

semaglutide

OzempicSingle-dose prefilled syringe

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, the syringe can be kept from 8°C to 30°C (46°F to 86°F) for up to 28 days. Keep it in the original carton until the time of administration.
After first use
Single use only. Discard the syringe after use.
Room-temperature window
Up to 28 days at 8°C to 30°C (46°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from light; keep in the original carton until use.
Label date
Revised 5/2026

Read the Ozempic label on DailyMed

semaglutide

WegovySingle-dose pen or single-dose prefilled syringe

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, before the cap is removed, it can be kept from 8°C to 30°C (46°F to 86°F) for up to 28 days. Keep it in the original carton until the time of administration.
After first use
Single use only. Discard the pen or syringe after use.
Room-temperature window
Up to 28 days at 8°C to 30°C (46°F to 86°F), before the cap is removed
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect the injection from light. Do not store in the freezer or directly next to the refrigerator's cooling element.
Label date
Revised 6/2026

Read the Wegovy label on DailyMed

semaglutide

WegovyFlexTouch single-patient-use pen (4 weekly doses of 2.4 mg)

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F) before first use. Do not store in the freezer or directly next to the refrigerator's cooling element.
After first use
After first use the pen can be stored for 56 days, either between 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Keep the pen cap on when not in use and store it with no needle attached.
Room-temperature window
56 days after first use, at 15°C to 30°C (59°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from excessive heat and light.
Label date
Revised 6/2026

Read the Wegovy label on DailyMed

semaglutide

WegovyTablets (oral)

Before first use
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). No refrigeration.
After first use
Store and dispense in the original bottle. Keep tablets in the original bottle until use to protect them from moisture.
Room-temperature window
Room temperature always: 20°C to 25°C (68°F to 77°F), excursions 15°C to 30°C (59°F to 86°F)
Light and moisture
The label sets controlled room temperature and gives no refrigeration or freezing instruction. Keep the tablets in the original bottle, in a dry place away from moisture.
Label date
Revised 6/2026

Read the Wegovy label on DailyMed

tirzepatide

MounjaroSingle-dose pen

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, each single-dose pen can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days.
After first use
Single use only. Discard the pen after use, and discard it after a total of 21 days at room temperature even if unused.
Room-temperature window
Up to a total of 21 days, not exceeding 30°C (86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; store in the original carton to protect from light.
Label date
Revised 4/2026

Read the Mounjaro label on DailyMed

tirzepatide

MounjaroSingle-dose vial

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, each single-dose vial can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days.
After first use
Single use only. Discard the vial after use, and discard it after a total of 21 days at room temperature even if unused.
Room-temperature window
Up to a total of 21 days, not exceeding 30°C (86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; store in the original carton to protect from light.
Label date
Revised 4/2026

Read the Mounjaro label on DailyMed

tirzepatide

MounjaroKwikPen single-patient-use pen, or multi-dose vial

Before first use
Unopened: refrigerate at 2°C to 8°C (36°F to 46°F), where it can be used until the expiration date on the label. If instead stored at room temperature up to 30°C (86°F), throw it away after 30 days.
After first use
Once opened, store in the original carton either refrigerated at 2°C to 8°C (36°F to 46°F) or at room temperature up to 30°C (86°F). Throw it away after a total of 30 days at room temperature, 30 days after first use, or after 4 weekly doses, whichever comes first, even if medicine is left in it.
Room-temperature window
30 days total at room temperature, up to 30°C (86°F); 30 days after first use either way
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; keep the opened device in the original carton.
Label date
Revised 4/2026

Read the Mounjaro label on DailyMed

tirzepatide

ZepboundSingle-dose pen

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, each single-dose pen can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days.
After first use
Single use only. Discard the pen after use, and discard it after a total of 21 days at room temperature even if unused.
Room-temperature window
Up to a total of 21 days, not exceeding 30°C (86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; store in the original carton to protect from light.
Label date
Revised 4/2026

Read the Zepbound label on DailyMed

tirzepatide

ZepboundSingle-dose vial

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F). If needed, each single-dose vial can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days.
After first use
Single use only. Discard the vial after use, and discard it after a total of 21 days at room temperature even if unused.
Room-temperature window
Up to a total of 21 days, not exceeding 30°C (86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; store in the original carton to protect from light.
Label date
Revised 4/2026

Read the Zepbound label on DailyMed

tirzepatide

ZepboundKwikPen single-patient-use pen, or multi-dose vial

Before first use
Unopened: refrigerate at 2°C to 8°C (36°F to 46°F), where it can be used until the expiration date on the label. If instead stored at room temperature up to 30°C (86°F), throw it away after 30 days.
After first use
Once opened, store in the original carton either refrigerated at 2°C to 8°C (36°F to 46°F) or at room temperature up to 30°C (86°F). Throw it away after a total of 30 days at room temperature, 30 days after first use, or after 4 weekly doses, whichever comes first, even if medicine is left in it.
Room-temperature window
30 days total at room temperature, up to 30°C (86°F); 30 days after first use either way
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from heat and light; keep the opened device in the original carton.
Label date
Revised 4/2026

Read the Zepbound label on DailyMed

semaglutide

RybelsusTablets (oral)

Before first use
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). No refrigeration.
After first use
Store and dispense in the original bottle. Keep tablets in the original bottle until use to protect them from moisture.
Room-temperature window
Room temperature always: 20°C to 25°C (68°F to 77°F), excursions 15°C to 30°C (59°F to 86°F)
Light and moisture
The label sets controlled room temperature and gives no refrigeration or freezing instruction. Store the product in a dry place away from moisture.
Label date
Revised 1/2026

Read the Rybelsus label on DailyMed

liraglutide

SaxendaSingle-patient-use pen (daily doses)

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F) before first use. Do not store in the freezer or directly next to the refrigerator's cooling element.
After first use
After initial use the pen can be stored for 30 days, either at controlled room temperature 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Keep the pen cap on when not in use and store it with no needle attached.
Room-temperature window
30 days after first use, at 15°C to 30°C (59°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from excessive heat and sunlight.
Label date
Revised 6/2026

Read the Saxenda label on DailyMed

liraglutide

VictozaSingle-patient-use pen (daily doses)

Before first use
Refrigerate at 2°C to 8°C (36°F to 46°F) before first use. Do not store in the freezer or directly next to the refrigerator's cooling element.
After first use
After first use the pen can be stored for 30 days, either at controlled room temperature 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Keep the pen cap on when not in use and store it with no needle attached.
Room-temperature window
30 days after first use, at 15°C to 30°C (59°F to 86°F)
Freezing
Do not freeze. If it has been frozen, do not use it — ask your pharmacist what to do with it.
Light and moisture
Protect from excessive heat and sunlight.
Label date
Revised 10/2025

Read the Victoza label on DailyMed

Questions people actually ask

How long can an Ozempic pen stay out of the fridge?
The Ozempic label says that after first use the single-patient-use pen can be kept for 56 days, either at controlled room temperature 15°C to 30°C (59°F to 86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Before first use it is a refrigerated product. The single-dose prefilled syringe is a different row: it can be kept from 8°C to 30°C (46°F to 86°F) for up to 28 days. Check which presentation is on your carton, and check the leaflet that came with it.
Can a Wegovy pen be left out overnight?
The Wegovy label allows the single-dose pen or syringe to be kept from 8°C to 30°C (46°F to 86°F) for up to 28 days before the cap is removed, and allows the FlexTouch single-patient-use pen 56 days after first use at 15°C to 30°C (59°F to 86°F). A night at room temperature falls inside those windows, but the windows are cumulative totals rather than a nightly allowance, and the label also says to protect the injection from light. If you are unsure whether a pen is still within its window, your pharmacist is the one to ask.
What room temperature does Mounjaro allow?
For the Mounjaro single-dose pen and single-dose vial, the label says each one can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days, and should be discarded after that even if unused. The KwikPen and the multi-dose vial are a different row: unopened they can be refrigerated until the expiration date, or thrown away after 30 days if stored at room temperature up to 30°C (86°F); once opened they are discarded after 30 days at room temperature, 30 days after first use, or four weekly doses, whichever comes first.
Can I pack a pen against an ice pack or freeze it?
No. Every injectable label in the table below says do not freeze, and several add that the pen must not sit directly next to the refrigerator's cooling element. A hard frozen gel pack pressed against a carton is the risk rather than the fix. If a pen has been frozen, the labels say not to use it — ask your pharmacist what to do with it.
Do the oral tablets need a fridge?
No. The Rybelsus and Wegovy tablet labels specify controlled room temperature — 20°C to 25°C (68°F to 77°F), with excursions permitted to 15°C to 30°C (59°F to 86°F) — and give no refrigeration instruction and no freeze statement. They say to store and dispense the tablets in the original bottle, which protects them from moisture.
What are the storage rules for compounded semaglutide or tirzepatide?
Compounded products have no FDA-approved label, so nothing on this page applies to them — follow the storage instructions from the pharmacy that dispensed yours, and ask them directly if the instructions are unclear.

Call your prescriber todayWhether a particular pen is still good after a warm afternoon in a car is a phone call, not a lookup.

Your pharmacist can answer that one; we cannot, and neither can a forum. This page gives no dosing, no timing, and no guidance on a missed dose — those belong to you and your prescriber. It claims nothing about any product protecting a medication’s potency.

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